Combining Methylphenidate and Clonidine: A CLINICALLY SOUND MEDICATION OPTION

  • WILENS T
  • SPENCER T
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Abstract

Discusses the effectiveness of clonidine in the treatment of attention deficit hyperactivity disorder (ADHD) spectrum disease, particularly when co-occurring tics, aggression, and hyperactivity/impulsivity is part of the picture. The combination of clonidine and methylphenidate (MPH) shows promise in both open trials and by its widespread clinical use. Cases of fatality in people receiving the combination have a paucity of supporting evidence, with prominent mitigating and extenuating circumstances nullifying any scientific attempts at an association. (PsycINFO Database Record (c) 2012 APA, all rights reserved).

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WILENS, T. E., & SPENCER, T. J. (1999). Combining Methylphenidate and Clonidine: A CLINICALLY SOUND MEDICATION OPTION. Journal of the American Academy of Child & Adolescent Psychiatry, 38(5), 614–616. https://doi.org/10.1097/00004583-199905000-00025

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