Inhalation sedation - an adjunct to improved dental care: Preliminary communication

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Abstract

This paper describes a double blind controlled comparison of 10% and 50% nitrous oxide in the sedation of children for dentistry. Both sedation groups compare favourably with a third group of unsedated children, in terms of heart rate changes occasioned by dentistry. However, 50% nitrous oxide was far superior to both 10% nitrous oxide and oxide and air when assessed by changes in the peripheral vasoconstrictive response to fear.

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Brook, A. H., Winder, M., Major, E., & Berman, D. S. (1979). Inhalation sedation - an adjunct to improved dental care: Preliminary communication. Journal of the Royal Society of Medicine, 72(10), 756–760. https://doi.org/10.1177/014107687907201012

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