Cerebral Ischemia in Diabetics and Oxidative Stress

Abstract

Cerebral ischemia is one of the major complications of diabetes. Eighty four percent of diabetics die from either heart disease or stroke (both cause cerebral ischemia). Diabetes-induced oxidative stress is one of the factors responsible for the secondary complications of diabetes. Oxidative stress also plays a key role in cerebral ischemic damage. In this chapter we provide a literature review of how cerebral ischemia-induced oxidative stress is exacerbated in diabetics. We also provide correlates of how this increased oxidative stress may be responsible for increased cerebral ischemia damage in diabetics © 2014 Elsevier Inc. All rights reserved.