Polylink: To support two-point linkage analysis in autotetraploids

Abstract

Summary: Polylink runs under Microsoft Windows (95 or later). It performs various calculations that are useful for investigating two-point linkage analysis for autopolyploids, based on the random chromosome pairing model. These include calculation of offspring phenotypic probabilities as functions of the recombination fraction, r calculation of theoretical standard errors for the maximum likelihood estimator of r and numerical computation of maximum likelihood estimates. It also includes simulation facilities.