The isopropylsulfinyl group: A useful chiral controller for the asymmetric aziridination of sulfinylimines and the organocatalytic allylation of hydrazones

Abstract

(Chemical Equation Presented) A comparative study shows that the isopropylsulfinyl group for which an enantiodivergent and highly diastereoselective approach is reported behaves better than the tert-butylsulfinyl and p-tolylsulfinyl groups, both in terms of reactivity and stereoselectivity in the Corey-Chaykovsky reaction of chiral sulfinylimines and the organocatalytic allylation of acyl hydrazones. © 2005 American Chemical Society.