Novel transferable β-lactam resistance with cephalosporinase characteristics in Salmonella enteritidis

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Abstract

An isolate of Salmonella enteritidis was found to produce a plasmid-encoded β-lactamase (DHA-1) that conferred resistance to extended-spectrum cephalosporins and cephamycins. The substrate and inhibition profiles of this enzyme resemble a class C β-lactamase. This is the first report of a plasmid-mediated cephalosporinase of this class in the Salmonella genus.

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Gaillot, O., Clément, C., Simonet, M., & Philippon, A. (1997). Novel transferable β-lactam resistance with cephalosporinase characteristics in Salmonella enteritidis. Journal of Antimicrobial Chemotherapy, 39(1), 85–87. https://doi.org/10.1093/jac/39.1.85

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