Simultaneous determination of dopamine and uric acid using a glassy carbon paste electrode modified with copper- para red complex

Abstract

A simple approach based on cyclic voltammetry (CV) was developed for the simultaneous determination of dopamine (DA) and uric acid (UA) in the presence of ascorbic acid (AA) using a modified glassy carbon paste electrode (GCPE). In the present study, analytical parameters were optimized and electrochemical performance of the modified electrode was investigated. The calibration curves were obtained over the range of 15.97-157.98 μmol L-1dopamine and 15.97-195.35 μmol L-1uric acid. Detection limits of 4.8 μmol L-1for dopamine and 3 μmol L-1for uric acid were obtained at pH 7.0. The modified electrode was used for the detection of dopamine and uric acid in the real samples such as human serum and urine samples.