A comprehensive review of the autoimmune pathogenesis of acquired hemophilia A

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Abstract

Acquired haemophilia A (AHA) constitutes the most frequent form of autoimmunity againts coagulation factors. The pathogenic basis of anti-FVIII autoantibodies production remains unknown and our narrative review explores the possible causes and provides an overview of evidence data.

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Pardos-Gea, J., Barquinero, J., Alvarez, I., Cortina, V., Martínez, I. G., Fernández, L. M., & Vidal, F. (2025, October 1). A comprehensive review of the autoimmune pathogenesis of acquired hemophilia A. Thrombosis Research. Elsevier Ltd. https://doi.org/10.1016/j.thromres.2025.109444

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