Abstract
Background: The aim of this study is to understand the energy requirements of photoreceptor neurons. Results: Glucose withdrawal causes photoreceptor death. Mitochondrial fuels and autophagy can enhance survival. Conclusion: Mitochondrial activity and substrates for anabolic activity are required for photoreceptor survival. Significance: Understanding the energy requirements of photoreceptors will contribute to understanding the basis of retinal disease. © 2011 by The American Society for Biochemistry and Molecular Biology, Inc.
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CITATION STYLE
Chertov, A. O., Holzhausen, L., Kuok, I. T., Couron, D., Parker, E., Linton, J. D., … Hurley, J. B. (2011). Roles of glucose in photoreceptor survival. Journal of Biological Chemistry, 286(40), 34700–34711. https://doi.org/10.1074/jbc.M111.279752
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