Journal ArticleOPEN ACCESS

Mouse Resistance Against Foot-and-Mouth Disease Virus Induced by Injections of Pyran

  • Richmond J
Infection and Immunity (1971) 3(2) 249-253
DOI: 10.1128/iai.3.2.249-253.1971
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Abstract

Mouse resistance to foot-and-mouth disease virus (FMDV) was induced by intraperitoneal injections of pyran copolymer. A biphasic pattern of protection occurred with greatest resistance 4 and 48 hr after injection of this polyanion. Viremia was not detectable in pretreated mice challenge-exposed with FMDV. Incubation of virus with pyran did not alter viral infectivity in mice or tissue culture. Serum interferon was demonstrated 1 and 2 days after pyran administration.

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Richmond, J. Y. (1971). Mouse Resistance Against Foot-and-Mouth Disease Virus Induced by Injections of Pyran. Infection and Immunity, 3(2), 249–253. https://doi.org/10.1128/iai.3.2.249-253.1971

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