scEpiAge: an age predictor highlighting single-cell ageing heterogeneity in mouse blood

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Abstract

Here, the authors generate a single-cell DNA methylation and transcriptome dataset from mouse peripheral blood samples, spanning a broad range of ages. They next develop scEpiAge, a single-cell DNA methylation age predictor.

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Bonder, M. J., Clark, S. J., Krueger, F., Luo, S., Agostinho de Sousa, J., Hashtroud, A. M., … von Meyenn, F. (2024). scEpiAge: an age predictor highlighting single-cell ageing heterogeneity in mouse blood. Nature Communications , 15(1). https://doi.org/10.1038/s41467-024-51833-5

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