Comparison of the detection and quantification of rabies antibodies in canine sera

Abstract

Rabies antibodies in canine sera were detected and quantified by methods: virus neutralisation test on mice (VNT), rapid fluorescence focus inhibition test (RFFIT), and fluorescent antibody virus neutralisation (FAVN). The results of rabies antibodies levels in non-vaccinated dogs obtained by all three methods were in correlation. The comparison of rabies antibody titres determined in vaccinated dogs using VNT and FAVN methods showed 86.6% correspondence, while those obtained by RFFIT and FAVN methods corresponded in almost 95% of cases.