Abstract
A new benzodiazepine, sclerotigenin (1), was isolated from organic extracts of the sclerotia of Penicillium sclerotigenum (NRRL 3461) along with two known griseofulvin analogues. The structure of 1 was determined primarily by analysis of 1H NMR, 13C NMR, HMQC, and HMBC data. Compound 1 was the major component of the CH2Cl2 extract of P. sclerotigenum sclerotia and is responsible for most of the antiinsectan activity of the extract against the crop pest Helicoverpa zea.
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CITATION STYLE
Joshi, B. K., Gloer, J. B., Wicklow, D. T., & Dowd, P. F. (1999). Sclerotigenin: A new antiinsectan benzodiazepine from the sclerotia of Penicillium sclerotigenum. Journal of Natural Products, 62(4), 650–652. https://doi.org/10.1021/np980511n
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