Cu/Fe-Catalyzed Carbon-Carbon and Carbon-Heteroatom Cross-Coupling Reactions

Abstract

Copper and iron salts are less toxic and  inexpensive as compared to other transition metal salts. These salts have been extensively used for various carbon-carbon and carbon-heteroatom cross-coupling reactions. In this review, we described the Cu and Fe-mediated C-C, C-N, C-O, C-S and C-Se coupling reactions extensively. The synergistic effects of copper and iron salts towards the various bond-forming reactions have been presented. Use of such methods in the synthesis of bioactive molecules were also highlighted.