Multidrug-resistant Pseudomonas aeruginosa strains in Tehran Reference Burn Hospital, Tehran, Iran

Abstract

Pseudomonas aeruginosa is one of the most common causes of burn woundinfections. The aim of this study was to determine the frequency ofantibiotic resistance burn morbidity during September 2005 to October2007. The incidence of multi-drug resistant P. aeruginosa infection wasindicated in 9238 patients admitted to Tehran Reference Burn Hospital.Specimens were collected after admitting the patients in the hospitalwards. Susceptibility test were performed for all isolate. Specimenswere collected based on hospital policy and cultures were performed oneach patient. Isolated strains were identified by using standardbacteriological methods for isolation and identification of thecausative agents. P. aeruginosa was identified in 3012 (70.5%),Staphylococcus aureus in 581 (13.6%), Acinetobacter 426 (9.9%), therest organisms were 279 (6%). Frequencies resistant of appliedantibiotics were tobramycin (82%), ceftazidim (78%), ceftizoxime(82%), ciprofloxacin (72%), amikacin (73%), gentamycin (80%),tetracyclin (60%), teazabactam (81%) and cotrimocxazol (98%),respectively for P. aeruginosa. Due to the high multi resistant rate inpseudomonas infection, there is need to immediately revise the hospitalpolicy in control of nosocomial infection and treatment strategy such asmore efficient antiseptic agents or new antibiotics used to reduce therate of multidrug resistant.