Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma

  • San Miguel J
  • Schlag R
  • Khuageva N
  • et al.
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Abstract

The standard treatment for patients with multiple myeloma who are not candidates for high-dose therapy is melphalan and prednisone. This phase 3 study compared the use of melphalan and prednisone with or without bortezomib in previously untreated patients with multiple myeloma who were ineligible for high-dose therapy.

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San Miguel, J. F., Schlag, R., Khuageva, N. K., Dimopoulos, M. A., Shpilberg, O., Kropff, M., … Richardson, P. G. (2008). Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma. New England Journal of Medicine, 359(9), 906–917. https://doi.org/10.1056/nejmoa0801479

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