Biotransformation of the phytoestrogen 8-prenylnaringenin

Abstract

In order to select microorganisms capable of transforming the potent phytoestrogen 8-prenylnaringenin, preliminary screening tests on 30 fungal cultures were performed. No reports concerning successful biotransformation of 8-prenylnaringenin by this class of organisms have been known so far. Fusarium equiseti converted 8-prenylnaringenin into 2"-(2"'-hydroxyisopropyl)-dihydrofuran-[2",3":7,8]-5,4'-dihydroxyflavanon in high yield. © 2010 Verlag der Zeitschrift für Naturforschung. Tübingen.