Abstract
The transmission of direct-acting antiviral resistance-associated substitutions (RAS) could hamper hepatitis C virus (HCV) cure rates and elimination efforts. A phylogenetic analysis of 87 men who have sex with men recently infected with HCV genotype 1a placed one-third (28/87) in a large cluster, in which 96% harbored NS5A M28V RAS.
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Popping, S., Verwijs, R., Cuypers, L., Claassen, M. A., Van Den Berk, G. E., De Weggheleire, A., … Florence, E. (2020). Transmission of NS5A-Inhibitor Resistance-Associated Substitutions among Men Who Have Sex with Men Recently Infected with Hepatitis C Virus Genotype 1a. Clinical Infectious Diseases, 71(8), E215–E217. https://doi.org/10.1093/cid/ciaa145
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