Drug resistance spread in 6 metropolitan regions, Germany, 2001-2018

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Abstract

We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy-naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg, Hannover, and Munich, Germany. Phylogenetic and network analysis elucidated numerous cases of shared drug resistance mutations among genetically linked patients; K103N was the most frequently shared mutation.

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Stecher, M., Chaillon, A., Stephan, C., Knops, E., Kohmer, N., Lehmann, C., … Hoenigl, M. (2020, October 1). Drug resistance spread in 6 metropolitan regions, Germany, 2001-2018. Emerging Infectious Diseases. Centers for Disease Control and Prevention (CDC). https://doi.org/10.3201/eid2610.191506

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