2-Ethyl-3-[(R)-2-phenylbutanamido]quinazolin-4(3H)-one monohydrate

Abstract

In the title compound, C20H21N3O 2·H2O (EQR·H2O), the quinazoline ring system forms dihedral angles of 53.1(1) and 85.6(1)° with the phenyl ring and the amide link, respectively. In the crystal, O-H..O hydrogen bonds link two EQR and two water molecules into a centrosymmetric R 4 4(18) ring motif. N-H..O hydrogen bonds further link these hydrogen-bonded fragments into columns extending in [010].