Landau-Kleffner syndrome

Abstract

Landau-Kleffner syndrome is one of several language disorders associated with epilepsy or epileptiform abnormalities on EEG. Ultimately, these patients understand little or nothing of what they hear. Two thirds have behavioral abnormalities and close to 75% have seizures. Brain computerized tomography and MRI are normal, EEG changes show characteristic epileptiform changes. Antiepileptic drugs can easily control seizures, but language recovery is more difficult. Autoimmune etiology is considered likely and long-term prognosis remains variable.