Role of hyaluronic acid during periodontal therapy & post-periodontal surgeries

Abstract

Hyaluronic acid (HA) is a glycosaminoglycan with a high molecular weight found abundantly in the extracellular matrix of soft periodontal tissues. HA has anti-bacterial & anti-inflammatory action in periodontitis & gingivitis. It is plausible that HA administration to diseased periodontal sites is beneficial during periodontal healing as well as post-surgical healing, thus aiding in the management of the periodontal disease. Data gathered from clinical evidence exhibits that HA’s tissue repairing and wound healing could be beneficial not only in patients affected by gingivitis and periodontitis but also during as well as post-periodontal surgery, with significant improvement in their quality of life. This review discusses the physicochemical, biochemical, and pharmacotherapeutic uses of HA during periodontal therapy as well as post-periodontal surgery.