Oropharyngeal carcinoma: A sexually transmitted disease

Abstract

Human papillomavirus (HPV)-associated oropharyngeal cancer (OPC) is on the increase and accounts for 18% to 63% of OPC. It occurs mostly in young males with no other identifiable risk factors. The vast majority of HPV-associated OPC is attributable to HPV16. The prognosis of patients with HPV-positive OPC is better than patients with HPV-negative OPC. Oral HPV infection is linked to sexual transmission. The natural history, prevalence and possible risk factors in local communities should be studied to implement appropriate prevention strategies. © SAAFP.