Abstract
A novel methodology for general and chemoselective preparation of non-symmetric 1,3,4-oxadiazoles is developed. This unusual reaction proceeds via polyphosphoric acid-assisted activation of nitroalkanes towards nucleophilic attack with acylhydrazides.
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CITATION STYLE
APA
Aksenov, A. V., Khamraev, V., Aksenov, N. A., Kirilov, N. K., Domenyuk, D. A., Zelensky, V. A., & Rubin, M. (2019). Electrophilic activation of nitroalkanes in efficient synthesis of 1,3,4-oxadiazoles. RSC Advances, 9(12), 6636–6642. https://doi.org/10.1039/c9ra00976k
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