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Lupus nephritis and beyond: Kidney-intrinsic genetic risk for antibody deposition

Cell Reports Medicine (2021) 2(12)
DOI: 10.1016/j.xcrm.2021.100479
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Abstract

Antibody deposition is a defining pathological feature of multiple kidney diseases including lupus nephritis. In this issue of Cell Reports Medicine, Jiang and colleagues1 identify a novel genetic risk factor, VANGL1, which predisposes individuals toward antibody deposition via a kidney-intrinsic mechanism.

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Chernova, I., & Craft, J. (2021). Lupus nephritis and beyond: Kidney-intrinsic genetic risk for antibody deposition. Cell Reports Medicine, 2(12). https://doi.org/10.1016/j.xcrm.2021.100479

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