Formation of (c-c)bonds catalyzed by vitamin b12

Abstract

Under reducing reaction conditions vitamin Bi12 and related cobalt complexes are powerful catalysts for the 1,4 addition of alkyl-,vinyl - and acyl derivatives to activated olefins. Several examples illustrate the intra-and intermolecular (C-C)bond formation. The reaction mechanism involves the formation and cleavage of a (Co-C)bond. © 1983 IUPAC