Catching filopodia: Exosomes surf on fast highways to enter cells

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Abstract

The mechanisms of exosomal uptake and their intracellular itinerary are not understood. In this issue, Heusermann et al. (2016. J Cell. Biol. http://dx.doi.org/10.1083/jcb.201506084) show that exosomes surf filopodia and are endocytosed in a process reminiscent to virus entry. Intraendosomal exosomes travel to the ER and are distributed to lysosomal compartments.

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APA

Schneider, A., & Simons, M. (2016). Catching filopodia: Exosomes surf on fast highways to enter cells. Journal of Cell Biology, 213(2), 143–145. https://doi.org/10.1083/jcb.201604024

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