Introduction to decision tree modeling

Abstract

This chapter consolidates the material on economic evaluation for vaccines throughout Section 3 with an applied case of hepatitis B vaccination. By following along with the construction of a simple decision tree and data parameter inputs, one should be able to accurately derive and interpret key resulting statistics of value for a common example in vaccine decision-making, including cost-effectiveness analysis, budget impact analysis, and return on investment calculations. By doing so, readers will have a working model that they can manipulate to explore their own version of value assessment, as well as be prepared to format economic statistics for decision makers preferences based on matters of efficiency, equity and affordability.