Synthesis of new 2-ferrocenyl-5-fluoro-6-(4-substituted-1-piperazinyl)-1H- benzimidazoles of potential biological interest

Abstract

New substituted 2-ferrocenylbenzimidazole derivatives are prepared by the oxidation of corresponding Schiffs bases in situ, generated from corresponding 1,2-diamino-4-fluoro-5-(1-piperazinyl)benzenes and 2-ferrocenecarboxaldehyde using nitrobenzene.