Effect of Azadirachta indica leaf extract on serum lipid profile changes in normal and streptozotocin induced diabetic rats

Abstract

Effects of Azadirachta indica leaf extract on serum lipid profile changes in normal and streptozotocin-induced diabetic rats have been studied with a view to elucidate its possible effect on cardiovascular disease induced by hyperglycemia. It was observed that A. indica leaf extract significantly reduced the total cholesterol, LDL-and VLDL-cholesterol, triglycerides and total lipids of serum in streptozotocin-induced diabetic rats but HDL-cholesterol levels remained unchanged when compared with streptozotocin-induced diabetic control animals.