A novel deposition method of PLGA nanoparticles on coronary stents

12Citations
Citations of this article
19Readers
Mendeley users who have this article in their library.

Abstract

Bare metal stents which were used to treat coronary artery disease have several biochemical problems. Polymer-based drug-eluting stents (DES) have opened up a new paradigm in the treatment of in-stent restenosis. Many studies and research programmes have proved that DES can prevent restenosis. In our study, paclitaxel-loaded poly (lactic-co-glycolic acid) (PLGA) nanoparticles have been deposited along the three dimensional scaffold of coronary stents by a method using self-assembling properties of colloidal particles. We found that the nanoparticles were deposited uniformly and closely packed. The amount of paclitaxel was easily controlled by the drug content of the nanoparticles and the deposition count.

Cite

CITATION STYLE

APA

Joo, J. ryang, Nam, H. Y., Nam, S. H., Baek, I., & Park, J. S. (2009). A novel deposition method of PLGA nanoparticles on coronary stents. Bulletin of the Korean Chemical Society, 30(5), 1085–1087. https://doi.org/10.5012/bkcs.2009.30.5.1085

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free