Catch those antibodies before they fall

Abstract

In this issue of Blood, Perreault et al showed decreasing total antibody levels over time in 15 repeat COVID-19 convalescent plasma (CCP) donors with at least 4 donations.1 The decrease was greatest between the final 2 time points reported, from days 70 to 84 to days 85 to 114, after disease onset. This decrease was time dependent and independent of donation number.