Enzyme-Linked Immunosorbent Assay (Elisa) for Detection of Antibodies to Mycobacterium Para-Tuberculosis in Cattle

Abstract

Paratuberculosis may be diagnosed by clinical, bacteriological and immunological methods, but so far only the demonstration of M. paratuberculosis is considered a definite proof of the infection. World-wide use is being made of the complement fixation (CF) test as a valuable immunological test for diagnosis of clinical cases, but its low specificity and sensitivity makes its value problematic in non-clinical cases.