Risks Versus Benefits of Using Aspirin, Magnesium Sulfate, Corticosteroids, and Progesterone during Pregnancy

Abstract

This chapter will discuss various prophylactic and therapeutic strategies based on a review of the literature that is based on the best evidence. In this way, we will know the effect of aspirin as a prophylactic measure in the prevention of severe preeclampsia. Then, we treat the impact of magnesium sulfate to significantly reduce intracranial hemorrhage and cerebral palsy. Following this, we examine the impact of corticosteroids in premature pregnancies in different clinical scenarios, demonstrating their efficacy in improving neonatal prognosis. Finally, we will see the effect of progesterone in reducing premature labor. The use of these strategies has allowed for an improvement in perinatal morbidity and mortality due to the intrinsic beneficial effects of these drugs, as well as a decrease in prematurity (aspirin and progesterone).