Suppression of feeding by intrahypothalamic implants of estradiol in male and female rats

Abstract

The effect of intrahypothalamic implants of crystalline estradiol benzoate (EB) on feeding was examined in gonadectomized male and female rats. With the exception of one animal, whose cannula terminated in the third ventricle, all sites at which EB produced substantial suppression of feeding were located in the ventromedial hypothalamic nuclei (VMH). There was no sex difference in the proportion of sites within the VMH at which EB implants suppressed feeding. © 1974, The Psychonomic Soceity, Inc.. All rights reserved.