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INCA033989: the first shot on goal for MPNs?

Blood
DOI: 10.1182/blood.2024026811
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Abstract

In this issue of Blood, Reis et al1 identify a monoclonal antibody, INCA033989, that selectively targets mutant calreticulin (mutCALR) in myeloproliferative neoplasms (MPNs), inhibiting its oncogenic activity without affecting normal hematopoiesis.

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Benlabiod, C., & Psaila, B. (2024, November 28). INCA033989: the first shot on goal for MPNs? Blood. Elsevier B.V. https://doi.org/10.1182/blood.2024026811

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