Illuminating the role of vitamin a in skin innate immunity and the skin microbiome: A narrative review

Abstract

Vitamin A is a fat-soluble vitamin that plays an important role in skin immunity. Deficien-cies in Vitamin A have been linked to impaired immune response and increased susceptibility to skin infections and inflammatory skin disease. This narrative review summarizes recent primary evidence that elucidates the role of vitamin A and its derivatives on innate immune regulators through mechanisms that promote skin immunity and sustain the skin microbiome.