GARLIC (ALLIUM SATIVUM) EXTRACT SUPPLEMENTATION ALTERS THE GLYCOGEN DEPOSITION IN LIVER AND PROTEIN METABOLISM IN GONADS OF FEMALE ALBINO RATS

Abstract

Garlic is an ayurvedic herb that has been extensively used as medication and as the taste enhancer of the food. The present investigation was undertaken to provide data on the efficacy of garlic (Allium sativum Linn.) extract on glycogen deposition and protein metabolism in female albino rats that may further explore medicinal potential of garlic. The rats were divided into four groups A, B, C and D, keeping group A as a healthy control. The garlic extract was tried in three different doses, 1ml, 2ml and 4ml/ kg body weight as low, medium and high dose respectively and given orally for the period of 7, 14, 21 and 28 days daily to the rats of group B, C and D as stated above. The significant (P<0.01 & P<0.05) increase in glycogen and protein level was observed when rats were fed with low and medium dose but when rats were fed with high dose of garlic extract there was significant (P<0.01) decrease in glycogen level and a not significant decrease in protein level was observed.