Disseminated Histoplasmosis in a Patient With Multiple Sclerosis Treated With Fingolimod

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Abstract

Histoplasma capsulatum is an endemic dimorphic fungus found in the central and eastern parts of the United States, leading to infection when conidia from soil or dust contaminated with bird or bat droppings are inhaled.1 Histoplasmosis can result in disseminated infection, with the gastrointestinal tract being a common site.2 We describe a case of histoplasmosis in a patient with multiple sclerosis (MS) on immunomodulatory therapy presenting with gastrointestinal disease.

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Abrahamowicz, A. A., Chow, E. J., Child, D. D., Dao, A., Morrison, E. D., Gill, S. K., … Garvin, K. (2021). Disseminated Histoplasmosis in a Patient With Multiple Sclerosis Treated With Fingolimod. Neurology: Neuroimmunology and NeuroInflammation, 8(3). https://doi.org/10.1212/NXI.0000000000000966

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