Bactericidal Effect of Different Anti-Microbial Agents on Fusobacterium Nucleatum Biofilm

  • Ashok R
  • Ganesh A
  • Deivanayagam K
N/ACitations
Citations of this article
12Readers
Mendeley users who have this article in their library.

Abstract

INTRODUCTION: The root canal anatomy of the teeth is very complex. Complete debridement of the root canals is a challenge and is very important for the success of the root canal treatment. Hence, this study was done to find an effective irrigant which can be used during root canal treatment. OBJECTIVE: The bactericidal effect of a potential root canal irrigant was compared with two commonly used root canal irrigants against monoculture biofilm of a commercially available isolate of Fusobacterium nucleatum. METHODS: A monoculture biofilm of Fusobacterium nucleatum was grown on glass slides. The glass slides containing the biofilm were immersed in centrifuge tubes containing 5% sodium hypochlorite, 2% Chlorhexidine, 6% turmeric solution, 9% turmeric solution and distilled water for a time span of one minute. A wire loop was used to scrape off the biofilms onto sterile brain heart infusion agar plates. This was further subjected to an incubation period of 96 hours at 37 degrees C. Colony forming units were quantified by statistical analysis and results were obtained. RESULTS: The anti-bacterial activity of 6% and 9% turmeric solution was statistically significant against Fusobacterium nucleatum when compared to 2% Chlorhexidine and 5% sodium hypochlorite. CONCLUSION: In endodontic treatment, turmeric solution may be considered as an effective irrigant.

Cite

CITATION STYLE

APA

Ashok, R., Ganesh, A., & Deivanayagam, K. (2017). Bactericidal Effect of Different Anti-Microbial Agents on Fusobacterium Nucleatum Biofilm. Cureus. https://doi.org/10.7759/cureus.1335

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free