A new hydroxy fatty acid sophoroside from Candida bogoriensis

Abstract

When cultured in stirred fermentors the yeast Candida bogoriensis produces extracellular glycolipids in yields of 0.5 to 1 g/l. The principal component of these is a crystalline sophorosyl hydroxy fatty acid, the structure of which has been established as 13-[(2′-O-β-D-glucopyranosyl-β-D-glucopyranosyl)-oxy]docosanoic acid 6′,6″-diacetate. The hydroxy acid portion of the molecule probably has the L-configuration. A monoacetyl glycolipid is also present as a minor component.