Effect of Doxorubicin on Histomorphology of Liver of Wistar Albino Rats

Abstract

Doxorubicin is associated with adverse effects on organs like liver. This study was done to find the effects of doxorubicin on liver of wistar albino rats. Sixty healthy wistar albino rats were taken for the study. The rats were randomly divided in to 4 groups (2 experimental groups; group A1 and A2, and 2 control groups; group B1and B2 each containing 16 rats). The experimental groups were given a single dose of doxorubicin ie 10 mg/kg body weight intraperitoneally and sacrificed after 7 days and 14 days for each group. Rats under control …