Abstract
The human heat-inducible Hsp70B and Hsp70B' genes were co-localized to 1q23.1 by in situ hybridization. However, though transcripts from Hsp70B could be detected in heat-shocked cells, DNA sequence analyses of both the gene and cDNA copies of the mRNA indicate the gene is non-functional. Moreover, mouse homologues of Hsp70B/B' were not detected by Southern blot analysis, suggesting Hsp70B/B' arose from either Hsp70-1or Hsp70-2 after the divergence of mice and humans.
Cite
CITATION STYLE
Parsian, A. J., Sheren, J. E., Tao, T. Y., Goswami, P. C., Malyapa, R., Van Rheeden, R., … Hunt, C. R. (2000). The human Hsp70B gene at the HSPA7 locus of chromosome 1 is transcribed but non-functional. Biochimica et Biophysica Acta, 1494(1–2), 201–205. https://doi.org/10.1016/s0167-4781(00)00203-7
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
