Conducting Chromatin Motion: Actin Dynamizes Contents of the Oocyte Nucleus

Abstract

Architecture of the nucleus is intimately linked to fundamental cellular processes carried out within it, such as maintenance of genome stability and gene expression. In this issue of Developmental Cell, Almonacid et al. (2019) show that actin-dependent shape fluctuations of the oocyte nucleus promote the movement of chromatin inside the nucleoplasm.