The Association between Amino Acid Intake and Polycystic Ovary Syndrome in Women Who Referred to Isfahan University of Medical Science Clinics

Abstract

Background and Objectives: Polycystic ovary syndrome (PCOS) is the greatest current endocrine disease in generative women. Although other issues such as insulin resistance, hyperinsulinemia, adiposity and dietary pattern are implied to be connected to PCOS, but the most recent evidence are needed to improve management of PCOS. Proteins and amino acids (key dietary components) can also have impact on this condition and may have therapeutic effects for handling this disorder. However, there is little information available in this area. So, the purpose of this study was to assess the connection between amino acids and protein intake and PCOS. Materials and Methods: Science, Iran. Amino acids and proteins intake was estimated using validated food frequency questionnaire. Other factors such as ovarian disease, inherited predisposition, physical activity, the age of menarche and medical history were assessed by the questionnaire. Data analysis was represented by adjusted logistic by SPSS software version 15. Results: The marked association among PCOS and ovarian disease (P < 0.001), age (P < 0.001) and consuming drugs (P = 0.001) were seen. There was inversely associated between body mass index (BMI) and PCOS, but it was not remarkable (P = 0.068). But, no statistically significant connection was seen between the use of LEU (Lucien), MET (methionine), CYS (cysteine), PHE (phenylalanine), VAL (valine), ASP (asparagines), GLU (glutamic acid), and PCOS. Although, there was significant relationship between glycine, prolin, and methionine with PCOS. Conclusions: According to the results of this study, significant relationship was observed between glycine, prolin, and methionine and BCAA/AAA ratio with PCOS.