Effect of medicaments used in endodontic regeneration technique on push-out bond strength of MTA and Biodentine

Abstract

The aim of the present study was to evaluate the effect of the intracanal medicaments used in regenerative endodontic treatment on push-out bond strength (PBS) of mineral trioxide aggregate (MTA) and Biodentine (BD). The root canals of 102 maxillary incisors were enlarged to simulate immature roots and were randomly divided into three groups (n = 34): a control group (no intracanal medicament) and two test groups, subjected to calcium hydroxide (CH) or triple antibiotic paste (TAP) medication for two weeks. After the medication removal, each group was divided in two subgroups and the coronal portion of each canal was filled with MTA or BD. After one week of storage, the coronal region of each root was horizontally sectioned and push-out test was performed. Data were analyzed by two-way analysis of variance and the Tukey post hoc test (P = 0.05). PBS values were significantly affected by the type of material (P < 0.001) and the type of medication used (P = 0.049), but no interaction was found (P = 0.97). The BD group showed significantly higher push-out resistance values than those of the MTA group (P < 0.001). TAP showed the lowest PBS values, which were significantly lower than those of the control group (P = 0.043) but not than those of CH (P = 0.229). After a two-week application period, TAP seemed to decrease the PBS of both cements, while CH did not. BD appeared to have higher PBS compared to MTA, regardless of medication.