Abstract
One of the most frequent and widespread infectious diseases especially in developing countries is tuberculosis (TB). The number of TB drug resistant tend to increase, and there has been no new TB drug introduce since the 1960s. Six 2-Thiophenecarboxylic acid hydrazide derivatives were synthesized in 90-97% yields, and 2-thiophenecarbonylhydrazone-5, 7-dibromoisatin showed the highest activity in inhibiting M. tuberculosis H37Rv.
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CITATION STYLE
Fahmi, M. R. G., Khumaidah, L., Ilmiah, T. K., Fadlan, A., & Santoso, M. (2018). 2-Thiophenecarboxylic acid hydrazide Derivatives: Synthesis and Anti-Tuberculosis Studies. In IOP Conference Series: Materials Science and Engineering (Vol. 349). Institute of Physics Publishing. https://doi.org/10.1088/1757-899X/349/1/012039
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