Long term persistence of coronavirus SARS-CoV-2 infection

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Abstract

During the COVID-19 pandemic, a case of a long-term persistence of SARS-CoV-2 infection (from March 26 to May 20, 2020) was identified at a private hospital in São Paulo, SP, Brazil. The long-term positivity for SARS-CoV-2 in reverse transcriptase polymerase chain reaction tests of a patient diagnosed with COVID-19 suggests, at least part of patients who recovered, may still carry and transmit the SARS-CoV-2 virus. This fact emphasizes the importance of having at least two negative reverse transcriptase polymerase chain reaction test results for SARS-CoV-2. Serological assays were not particularly helpful in the case described, since the patient had very low antibodies titers at the end of the follow-up period. Low viral loads may not be detected by current molecular methods, leading to wrong conclusions regarding viral clearance.

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APA

Pinho, J. R. R., Oliveira, K. G. de, Sitnik, R., Maluf, M. M., Rodrigues, P. H. S., Santana, R. A. F., … Irony, O. (2021). Long term persistence of coronavirus SARS-CoV-2 infection. Einstein (Sao Paulo, Brazil), 19, eRC6369. https://doi.org/10.31744/einstein_journal/2021RC6369

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