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Endoscopic evaluation of the gastrotolerance of short-term antalgic treatment with low dose K-diclofenac: A comparison of ibuprofen and aspirin

Fundamental and Clinical Pharmacology (2001) 15(1) 61-63
DOI: 10.1046/j.1472-8206.2001.00004.x
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Abstract

In a short-term gastro-duodenal endoscopic study in 12 healthy volunteers, the gastrotoxicity was not different after intake of diclofenac-K 12.5 mg (0.33) or ibuprofen 200 mg (0.42, P = 0.66) but significantly higher after aspirin 500 mg (2.67, P = 0.002).

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Mahé, I., Mouly, S., Mahé, E., Diemer, M., Knellwolf, A. L., Simoneau, G., … Bergmann, J. F. (2001). Endoscopic evaluation of the gastrotolerance of short-term antalgic treatment with low dose K-diclofenac: A comparison of ibuprofen and aspirin. Fundamental and Clinical Pharmacology, 15(1), 61–63. https://doi.org/10.1046/j.1472-8206.2001.00004.x

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