In vitro anti-oxidant activity of Ruellia tuberosa root extracts

Abstract

The present study was investigating the antioxidant activities of the various fractions of the hydromethanolic extract of the roots of Coccinia grandis L. Voigt. (Cucurbitaceae). The antioxidant activities of the fractions have been evaluated by using in vitro assays and were compared to standard antioxidants such as ascorbic acid, α-tocopherol, curcumin and butylated hydroxyl toluene (BHT). All the fractions showed effective H donor activity, reducing power, free radical scavenging activity etc. The antioxidant property depends upon concentration and increased with increasing amount of the fractions. The free radical scavenging and antioxidant activities may be attributed to the presence of phenolic and flavonoid compounds present in the fractions. The results obtained in the present study indicate that the roots of C. grandis are a potential source of natural antioxidant. © 2011 IGJPS. All rights reserved.